Related Experiment Video
Updated: May 7, 2026

A Mass Spectrometry-Based Proteomics Approach for Global and High-Confidence Protein R-Methylation Analysis
Published on: April 28, 2022
Absorption of L-methionine from the human small intestine
Abstract:
Absorption of L-methionine was measured in all parts of the human small intestine using transintestinal intubation and perfusion. In four normal subjects, adsorption was higher in the proximal than in the distal intestine. In two patients with nontropical sprue in relapse, there was a proximal zone of low absorption with higher absorption distally. In all parts of the small intestine, absorption showed rate-limiting kinetics as methionine concentration was increased. In normal subjects, the proximal K(m) (Michaelis constant) was more than 3 times higher than the distal, which suggests a difference in transport mechanisms between the two segments.
More Related Videos
07:39Cell-Type Specific Protein Purification and Identification from Complex Tissues Using a Mutant Methionine tRNA Synthetase Mouse Line
Published on: April 13, 2022
04:40Author Spotlight: Experiential Tool for Teaching Active Transport Using Ex Vivo Histidine Uptake
Published on: October 4, 2024
Related Concept Videos
Carbohydrate Absorption
After being swallowed, the partially digested carbohydrates mix with gastric secretions in the stomach. However, the acidic environment...
Protein Absorption
Lipid Absorption
These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
Phase II Reactions: Methylation Reactions
The mechanism of methylation unfolds in two stages. The first stage sees a methyltransferase enzyme facilitating the transfer of a methyl group from S-adenosylmethionine (SAM) to the substrate, forming S-adenosylhomocysteine (SAH). The second stage involves further metabolism of SAH into homocysteine, which can be recycled...
Absorption of Nutrients
Enterocytes, which are specialized polar epithelial cells, line the mucosa of the small intestinal walls. These cells...
Sulfur Assimilation