Related Experiment Videos
New ketosteroids from the red alga Hypnea musciformis
V Bultel-Poncé1, S Etahiri, M Guyot
1Laboratoire de Chimie des Substances Naturelles associé au CNRS, Muséum National d'Histoire Naturelle, 63 rue Buffon, 75005 Paris, France. bultel@mnhn.fr
Bioorganic & Medicinal Chemistry Letters
|June 18, 2002
Abstract:
The dichloromethane/methanol extract from the red alga Hypnea musciformis exhibited PPE elastase inhibition. A diketosteroid, the 20-hydroxy-5alpha-cholest-22-ene-3,6-dione was responsible for this activity. Two new steroids were isolated, 2 was assigned as the 6alpha-hydroxy-cholest-4-ene-3-one and 3 as the 6alpha-hydroxy-cholest-4,22-diene-3-one. The structures were assigned mainly on the basis of 1H and 13C NMR experiments.