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Published on: June 28, 2018
Stenotrophomonas maltophilia meningitis, bacteremia and respiratory infection
Evangelia Platsouka1, Christina Routsi, Anastasios Chalkis
1Department of Clinical Microbiology, Medical School of Athens University, Greece.
Abstract:
Stenotrophomonas maltophilia is an increasingly recognized cause of nosocomial infection of special interest because of its resistance to multiple antimicrobial agents. We report a case of generalized infection by S. maltophilia, including meningitis, bacteremia and respiratory tract infection, in a patient who had undergone multiple neurosurgical procedures and who was treated with trimethoprim-sulphamethoxazole.
Insights
Stenotrophomonas maltophilia causes difficult-to-treat nosocomial infections due to antimicrobial resistance. This case highlights a generalized S. maltophilia infection, including meningitis, successfully treated with trimethoprim-sulphamethoxazole.
Area of Science:
- Infectious Diseases
- Microbiology
- Neurosurgery
Background:
- Stenotrophomonas maltophilia is an emerging pathogen causing hospital-acquired infections.
- Its intrinsic resistance to multiple antibiotics poses significant treatment challenges.
Observation:
- A patient with a history of multiple neurosurgical procedures developed a generalized S. maltophilia infection.
- The infection encompassed meningitis, bacteremia, and respiratory tract involvement.
Findings:
- The case demonstrates a severe, multi-site infection caused by S. maltophilia.
- Successful treatment was achieved using trimethoprim-sulphamethoxazole.
Implications:
- This case underscores the importance of recognizing S. maltophilia as a cause of severe nosocomial infections.
- Trimethoprim-sulphamethoxazole remains a viable treatment option for susceptible S. maltophilia strains.
- Effective management requires prompt diagnosis and targeted antimicrobial therapy in immunocompromised or post-surgical patients.
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