Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A theoretical study of model lipid monolayers.

A Ivanova1, A Tadjer, B Radoev

  • 1Department of Physical Chemistry, University of Sofia, Bulgaria. fhai@chem.uni-sofia.bg

SAR and QSAR in Environmental Research
|June 20, 2002
PubMed
Summary

This study uses computational chemistry to model lipid molecules at the air/water interface. Results show how molecular structure influences lipid domain formation and headgroup area, aligning with experimental data.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precision Measurement of Neutrino Oscillation Parameters with 10 Years of Data from the NOvA Experiment.

Physical review letters·2026
Same author

Dual-Baseline Search for Active-to-Sterile Neutrino Oscillations in NOvA.

Physical review letters·2025
Same author

Studies on the significance of secretory IgA antibodies in the pathogenesis and clinical course of enterobiasis in infected persons from Bulgaria: preliminary findings.

Helminthologia·2025
Same author

Search for CP-Violating Neutrino Nonstandard Interactions with the NOvA Experiment.

Physical review letters·2024
Same author

INFLAMMATORY FACTORS IN DISSECTION OF THORACIC AORTIC ANEURYSM.

Georgian medical news·2024
Same author

Comparison of Preimplantation Mouse Embryos with Different Genetic Backgrounds as Models for Evaluating Human Embryo Culture Media Composition.

Reproductive sciences (Thousand Oaks, Calif.)·2024

Area of Science:

  • Physical Chemistry
  • Surface Science
  • Computational Chemistry

Background:

  • Phospholipid monolayers are crucial for understanding physicochemical properties controlled by molecular structure.
  • Previous studies focused on composition-property relationships and molecular-level structural variations.

Purpose of the Study:

  • To investigate model lipid molecules adsorbed on the air/water interface.
  • To understand how molecular structure and ionization affect lipid monolayers.
  • To compare theoretical calculations with experimental data.

Main Methods:

  • Semi-empirical (AM1) quantum chemical calculations were performed on molecular clusters.
  • Model lipid molecules were studied at the air/water interface.
  • Calculated results were compared with experimental data.

Related Experiment Videos

Main Results:

  • Optimized acidic molecules demonstrated a tendency to form domains.
  • Increased surfactant molecules in a cluster decreased effective headgroup area.
  • Increased ionization degree led to an increase in molecular area.

Conclusions:

  • The theoretical approach accurately describes monolayer behavior at the molecular level.
  • Findings align with experimental trends and electrostatic theory.
  • This method provides a reliable molecular-level understanding of traditionally phenomenological studies.