[Treatment of pseudomonas infection following burn injuries with specific antitoxic Ig-therapy]

The mortality rate of mice after standardized Pseudomonas infection was increased by preinjection of a sublethal dose of burn toxin. This effect was eliminated by a specific antitoxic Ig. After a sublethal burn followed by infection, 60% of the animals died, while treatment with specific Ig reduced the mortality rate to 3.3%. This might be a new way to improve the treatment of severely burned patients.