[Effect of arginine on insulin liberation during intra-abdominal operations]

During abdominal surgery the basal and glucose stimulated insulin secretion rate is reduced. An arginine-infusion of 0,5 g/kg over 30 minutes is able to stimulate the basal as well as the glucose stimulated insulin secretion under stress condition. A synergism between the effect of arginine and blood glucose concentration concerning the influence on insulin secretion can be proven. The results are important for the postoperative (posttraumatic) infusion therapy.