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Related Experiment Videos

Polypoidal choroidal vasculopathy with large vascular network.

Hisashi Tateiwa1, Sachiko Kuroiwa, Satoko Gaun

  • 1Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|June 20, 2002
PubMed
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Large polypoidal choroidal vasculopathy (PCV) involves extensive vascular networks and can mimic choroidal neovascularization. Distinguishing these cases from exudative age-related macular degeneration is challenging, despite typical PCV findings.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Vascular Biology

Background:

  • Polypoidal choroidal vasculopathy (PCV) is a subtype of exudative maculopathy.
  • Large vascular networks in PCV can present unique diagnostic challenges.

Purpose of the Study:

  • To characterize polypoidal choroidal vasculopathy (PCV) with large vascular networks spanning the retinal vascular arcade.
  • To investigate the clinical and angiographic features of these extensive PCV lesions.

Main Methods:

  • Retrospective analysis of 12 eyes with large PCV lesions from a cohort of 60 diagnosed cases.
  • Utilized fluorescein and indocyanine green (ICG) angiography for detailed vascular assessment.

Main Results:

  • Large PCV cases exhibited dilated, radially spreading network vessels with clustered polypoidal dilations.

Related Experiment Videos

  • Lesions frequently caused significant serous and/or hemorrhagic pigment epithelial detachments (PEDs).
  • Five cases showed rapid lesion expansion, with ICG revealing underlying mesh-like choroidal vessels.

    • Conclusions:

    • PCV with large vascular networks is a recognized entity, sometimes exhibiting features of choroidal neovascularization.
    • Differentiation from exudative age-related macular degeneration can be difficult, even with characteristic PCV findings on ICG angiography.