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Updated: Sep 30, 2026

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
Published on: December 3, 2016
Avascular necrosis of the epiphysis of the first metatarsal bone
G Souverijns1, P Peene, P Cleeren
1Department of Radiology, Virga Jesse Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.
Abstract:
We report a case of avascular necrosis of the epiphysis of the right first metatarsal in a 6-year-old boy. Radiographs showed sclerosis, collapse and a crescent sign in the epiphysis. The diagnosis was confirmed by magnetic resonance imaging and scintigraphy. Arch support was the therapy of choice. Six months after the onset of symptoms, a definite reossification was present. To our knowledge, this is the first radiological report of avascular necrosis of the epiphysis of the first metatarsal bone in the world literature, which prompted a review of the osteochondroses and their etiology.
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