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In vivo real-time intravascular MRI
Pedro A Rivas1, Krishna S Nayak, Greig C Scott
1Division of Cardiovascular Medicine, Stanford University School of Medicine, CA 94305-5233, USA.
Summary
Real-time Magnetic Resonance Imaging (MRI) with novel low-profile coils enhances intravascular imaging. This technique minimizes motion artifacts and improves visualization for catheter-based interventions.
Area of Science:
- Medical Imaging
- Biomedical Engineering
Background:
- Magnetic Resonance Imaging (MRI) is an evolving technology for catheter-based procedures.
- Overcoming catheter and physiological motion is crucial for effective intravascular imaging.
Purpose of the Study:
- To evaluate real-time MRI for intravascular imaging.
- To assess the performance of novel low-profile catheter coils.
Main Methods:
- Utilized a 1.5 T MRI scanner with high-speed gradients.
- Developed and tested low-profile, stub-matched catheter coils.
- Implemented an interleaved spiral sequence for real-time data acquisition, reconstruction, and display, incorporating off-slice saturation pulses for "black-blood" imaging.
Main Results:
- Achieved 120-440 micron resolution at up to 16 frames per second.
- Low-profile coils demonstrated comparable Signal-to-Noise Ratio (SNR) to traditional designs.
- Demonstrated effective blood signal suppression and visualization of vessel walls in phantom and in vivo rabbit aorta studies with minimal motion artifacts.
Conclusions:
- Real-time intravascular MRI with low-profile coil designs significantly advances imaging capabilities.
- The developed system offers enhanced visualization for catheter-based interventions.