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Updated: Aug 16, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Chiral hybrid metal-organic dendrimers
Hua Jiang1, Suk Joong Lee, Wenbin Lin
1Department of Chemistry, CB #3290, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
Abstract:
[structure: see text] New chiral terpyridines containing Frechét-type dendrons have been readily synthesized by coupling dendritic benzyl bromide and 4'-[6-(2,2'-dihydroxy-1,1'-binaphthyl)]-2,2':6'2' '-terpyridine. These chiral dendritic terpyridines were used to efficiently construct high molecular weight hybrid metal-organic dendrimers based on the Ru(II)-bis(terpy) linkage. Preliminary fluorescence measurements show generation-dependent fluorescence quenching behavior of 3,5-dimethoxybenzyl peripherals by the [Ru(terpy)(2)](2+) unit.
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