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Measurement of Lifespan in Drosophila melanogaster
Published on: January 7, 2013
Lifespan does not measure ageing
1Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany. kowald@molgen.mpg.de
Abstract:
The Gompertz equation, which describes the increase of mortality over time, is often used to measure the rate of the ageing process. However, a recent article argued that it is incorrect to use the function for this purpose and that its use should therefore be discouraged (Driver 2001). I believe that this conclusion is based on misunderstandings and that the Gompertz function (if used appropriately) is actually well suited to measure the ageing rate. Here I will solve the 'paradox' posed by the author and argue that it is actually lifespan that is inadequate to measure ageing and not the Gompertz function.
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