Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperpnea and Hyperventilation01:25

Hyperpnea and Hyperventilation

Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cochrane Airways Group reviews were prioritized for updating using a pragmatic approach.

Journal of clinical epidemiology·2014
Same author

Nitrous oxide cryotherapy for primary periocular basal cell carcinoma: outcome at 5 years follow-up.

The British journal of ophthalmology·2010
Same author

Open-label, ascending dose, prospective cohort study evaluating the antiviral efficacy of Rosuvastatin therapy in serum and lipid fractions in patients with chronic hepatitis C.

Journal of viral hepatitis·2010
Same author

Fluticasone versus placebo for chronic asthma in adults and children.

The Cochrane database of systematic reviews·2005
Same author

Inhaled fluticasone at different doses for chronic asthma in adults and children.

The Cochrane database of systematic reviews·2005
Same author

Cardioselective beta-blockers for chronic obstructive pulmonary disease.

The Cochrane database of systematic reviews·2002

Related Experiment Video

Updated: Jul 19, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Continuous positive airways pressure for obstructive sleep apnoea.

J White1, C Cates, J Wright

  • 1Respiratory Medicne, York District Hospital, Wigginton Rd, York, North Yorks, UK, YO31 8HE. john.white@excha.yhs-tr.northy.nhs.uk

The Cochrane Database of Systematic Reviews
|June 22, 2002
PubMed
Summary

Continuous positive airway pressure (CPAP) effectively treats obstructive sleep apnea, improving sleepiness and quality of life compared to placebo. However, patients often prefer oral appliances over CPAP, despite CPAP

More Related Videos

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
07:15

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

Related Experiment Videos

Last Updated: Jul 19, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
07:15

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation

Published on: December 5, 2025

Area of Science:

  • Sleep Medicine
  • Respiratory Medicine
  • Clinical Trials

Background:

  • Obstructive sleep apnea (OSA) involves airway narrowing during sleep, leading to breathing cessation (apnea) or reduction (hypopnea).
  • OSA is associated with daytime sleepiness, premature mortality, hypertension, ischemic heart disease, stroke, and accidents.
  • Continuous positive airway pressure (CPAP) is a primary treatment for OSA.

Purpose of the Study:

  • To evaluate the efficacy of CPAP in treating adult obstructive sleep apnea.
  • To compare CPAP treatment with placebo and oral appliances.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) sourced from major databases (MEDLINE, Embase, Cinahl) and expert consultation.
  • Included 12 RCTs with 475 participants meeting criteria for OSA and an apnea/hypopnea index >5/hour.
  • Data extraction and quality assessment were performed by two independent reviewers, with author contact for missing information.

Main Results:

  • CPAP significantly improved objective and subjective sleepiness, quality of life, and depression measures compared to placebo.
  • No significant effect of CPAP on daytime blood pressure was observed.
  • CPAP demonstrated superior improvement in apnea/hypopnea index and minimum oxygen saturation versus oral appliances, though patients preferred oral appliances.

Conclusions:

  • CPAP is more effective than placebo for improving sleepiness and quality of life in OSA patients.
  • CPAP offers greater respiratory disturbance improvement than oral appliances.
  • Patient preference favors oral appliances over CPAP, despite CPAP's clinical benefits.