[Permeability of post-ischemic aortic wall in rats]

Examinations were carried out in order to reveal details of process of the permeability damage, its degrea and fate of the plasma-substances getting into the vessel all. Abdominal aorta has been cross-clapped for one hour by the aid of a double ligature. In a recirculatory period from 1 hour to 10 days material serving for labeling of the plasma has been determined in the vessel using histochemical and microchemical methods. Colloidal iron was administered to animals one hour before removing the aorta. The highest quantity of colloidal iron in the aortic wall could be revealed after 24--48 hours of recirculation. By the 10th day the vessel wall contained physiological iron quantity. Colloidal iron administered on the second day of recirculation--when damage to permeability is most marked--in the early phase could be seen in the whole aortic wall. By the 7th day it could be detected only in the outer part of media and in the adventitia. Endothelium inhibits the flow of plasma-substances into the vessel wall, when they got through it, only elastic lamina form a temporary mechanical obstacle for transfusion.