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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
Autoimmune related pancreatitis.
1Department of Gastroenterology and Endoscopic Medicine, Kyoto University Hospital, Kyoto, Japan. okak@kuhp.kyoto-u.ac.jp
Autoimmune pancreatitis is a newly recognized condition associated with hypergammaglobulinaemia. This article reviews the concept and recent developments in understanding this distinct form of pancreatitis.
Area of Science:
- Gastroenterology
- Immunology
- Pathology
Background:
- The concept of autoimmune pancreatitis emerged following reports of unique pancreatitis cases.
- These cases presented with hypergammaglobulinaemia, suggesting an immune-mediated etiology.
Purpose of the Study:
- To discuss the emerging concept of autoimmune pancreatitis.
- To review recent literature and clinical observations regarding this condition.
Main Methods:
- Literature review of documented cases and relevant studies.
- Synthesis of clinical and pathological findings associated with autoimmune pancreatitis.
Main Results:
- Several cases consistent with autoimmune pancreatitis have been reported since the initial documentation.
- The condition is characterized by hypergammaglobulinaemia and specific pancreatic findings.
Conclusions:
- Autoimmune pancreatitis is a distinct clinicopathological entity.
- While not universally accepted, the concept warrants further investigation and recognition.
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