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Crystallization and preliminary structural analysis of an antibody complex formed with PfMSP1-19, a malaria vaccine

J C Pizarro1, V Chitarra, C Calvet

  • 1Unité d'Immunologie Structurale, CNRS URA 2185, Institut Pasteur, 25 Rue du Dr Roux, 75724 Paris, France.

Acta Crystallographica. Section D, Biological Crystallography
|June 22, 2002
PubMed

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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...