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Providing saline reacting anti-D cell typing reagent
Since 1969, when anti-D specific IgG was made available to protect recently delivered D negative women from sensitisation by fetal D positive cells, the supply of saline acting anti-D, suitable for reagent use has diminished. The same immunized male blood donors that provide the anti-D for the production of the specific IgG used for prophylaxis may, when bled up to fourteen days after restimulation, provide a source of saline anti-D suitable for reagent use. The results of such a procedure in 12 donors are described.
Since 1969, when anti-D specific IgG was made available to protect recently delivered D negative women from sensitisation by fetal D positive cells, the supply of saline acting anti-D, suitable for reagent use has diminished. The same immunized male blood donors that provide the anti-D for the production of the specific IgG used for prophylaxis may, when bled up to fourteen days after restimulation, provide a source of saline anti-D suitable for reagent use. The results of such a procedure in 12 donors are described.