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A rare case of ulcerative colitis complicating Wilson's disease: possible association between the two diseases
Takahiro Torisu1, Motohiro Esaki, Takayuki Matsumoto
1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. mesaki@intmed2.med.kyushu-u.ac.jp
Journal of Clinical Gastroenterology
|June 25, 2002
Abstract:
A case of ulcerative colitis complicated by Wilson's disease is described. In this case, ulcerative colitis occurred 12 years after the diagnosis of Wilson's disease, and the colitis was intractable to prednisolone and salazosulfapyridine. Because copper is one of the trace elements necessary for antioxidant defenses during inflammatory process, altered copper metabolism may have contributed to the intractability of the ulcerative colitis in this case.