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Serum lipid profiles in Japanese women and men during consumption of walnuts
M Iwamoto1, K Imaizumi, M Sato
1Laboratory of Nutrition Chemistry, Division of Bioresource and Bioenvironmental Sciences, Graduate School, Kyushu University, Fukuoka, Japan.
Objective:
To determine the serum cholesterol, apolipoproteins and LDL oxidizability in young Japanese women and men during walnut consumption and to evaluate its active principle.
Design:
Experimental study with a randomized design.
Subjects:
Twenty healthy women and 20 healthy men.
Interventions:
Subjects were randomly assigned to consume each of two mixed natural diets for 4 weeks in a cross-over design. Reference and walnut diets were designed and the walnut diet had 12.5% of the energy derived from walnuts (44-58 g/day).
Results:
The total cholesterol and serum apolipoprotein B concentrations, and the ratio of LDL cholesterol to HDL cholesterol was significantly lowered in women and men when fed on the walnut diet, than when on the reference diet (P
Conclusions:
alpha-Linolenic acid in the walnut diet appears to be responsible for the lowering of LDL cholesterol in women.
Sponsorship:
Kyushu University (Fukuoka, Japan) and the California Walnut Commission (California, USA).
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