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[Cerebral venous thrombosis and Behcet's disease]
Fériel el Bahri Ben Mrad1, Mohamed Fredj, Leila Skandrani
1Service de Neurologie, EPS Charles Nicolle, 1006 Tunis.
Insights
Behcet's disease can cause intracranial hypertension due to cerebral venous sinus thrombosis. MRI is crucial for diagnosing and evaluating this neurological complication.
Area of Science:
- Neurology
- Vascular Neurology
- Rheumatology
Context:
- Behcet's disease is a multisystem disorder with frequent neurological complications.
- Cerebral venous sinus thrombosis (CVST) is a serious neurological manifestation of Behcet's disease.
- Intracranial hypertension is a key symptom of CVST.
Purpose:
- To report cases of Behcet's disease presenting with symptomatic intracranial hypertension secondary to CVST.
- To highlight the diagnostic utility of MRI and angio-MRI in CVST.
- To emphasize the importance of timely diagnosis and management of CVST in Behcet's disease.
Summary:
- Four cases of Behcet's disease with intracranial hypertension due to CVST are presented.
- Patients experienced symptoms like headache, papilledema, seizures, and pyramidal syndromes.
- While CT scans showed non-specific findings, MRI confirmed CVST in three cases.
Impact:
- Highlights the significance of considering CVST in Behcet's disease patients with neurological symptoms.
- Underscores the diagnostic superiority of MRI and angio-MRI for CVST.
- Informs clinical practice regarding the evaluation and management of neurological complications in Behcet's disease.
Abstract:
Behcet's disease is a chronic relapsing multisystem disorder of unknown etiology. Neurological complications are frequent, occurring in 10 to 49% of cases. We report 4 cases with Behcet's disease (3 females and 1 male) who had symptomatic intracranial hypertension due to cerebral venous sinus thrombosis within a mean delay of 2 years. The mean age at onset was 31 years and the mean age on referral was 39.5 years. The predominant manifestation in our series were headache, papilledema, seizures and pyramidal syndromes. CT Scan showed non specific abnormalities in all of them and the sinus venous thrombosis was confirmed by MRI in 3 cases. The authors emphasize on the importance of MRI with angio MRI for the diagnosis, the outcome and the evaluation of the cerebral venous thrombosis after treatment.