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[Relationship between hypotension during hemodialysis and autonomic dysfunction in diabetic hemodialysis patients]
1Department of Nephrology, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Objective:
To observe the change of autonomic nerve function in diabetes mellitus(DM) patients who receive hemodialysis and to explore the relationship between this change and hypotension during hemodialysis.
Methods:
Twenty-five DM patients and 40 chronic glomerulonephritis(CGN) patients who received hemodialysis were checked. We tested their coefficient of variation R-R(CVR-R) in ECG, difference of systolic blood pressure between lying and standing positions, and serum parathyroid hormone(PTH); monitored the decrease of blood pressure during hemodialysis.
Results:
The rate(80.0%) of autonomic dysfunction(AD) in DM group is significantly higher than that(57.5%, P < 0.05) in CGN group. The rate(37.2%) of hypotension in those who had AD was significantly higher than that(18.2%, P < 0.05) in those who had normal autonomic nerve function during hemodialysis. No significant difference was found in PTH between each group.
Conclusion:
DM patients who receive hemodialysis are often complicated with AD, which is one of the reasons that causes hypotension during hemodialysis.