Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Ceramic-like xenogeneic bone combining with bone marrow].

Y Li1, Z Yang

  • 1Department of Orthopedic Surgery, First University Hospital, West China University of Medical Sciences, Chengdu, Sichuan, P. R. China 610041.

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery
|June 26, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protective immunity induced by B7/CD28-costimulated gamma delta T cells to the EL-4 lymphoma in allogenic athymic mice.

Journal of immunology (Baltimore, Md. : 1950)·1995
Same author

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase.

Nature genetics·1995
Same author

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

Proceedings of the National Academy of Sciences of the United States of America·1995
Same author

Artificial regulation of gene expression in Escherichia coli by RNase P.

Proceedings of the National Academy of Sciences of the United States of America·1995
Same author

Comparison of [3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity.

Journal of immunological methods·1995
Same author

Thermodynamic and activation parameters for binding of a pyrene-labeled substrate by the Tetrahymena ribozyme: docking is not diffusion-controlled and is driven by a favorable entropy change.

Biochemistry·1995
Same journal

[Research progress of electroactivity graphene-based materials in bone repair].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2026
Same journal

[Research advances in nerve transfer for upper limb function restoration: applications from peripheral nerve injury to central nervous system injury].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2026
Same journal

[Research progress of lymphaticovenous anastomosis in treatment of severe extremity trauma].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2026
Same journal

[Research progress of photoacoustic imaging in diagnosis of limb lymphedema].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2026
Same journal

[An integrated electrical stimulation-drug iontophoresis-monitoring system for tendon injury repair].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2026
Same journal

[A study on effect of a novel total nutritional composition for repairing full-thickness skin defects in rats].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2026
See all related articles

Ceramic-like xenogeneic bone (CXB) combined with bone marrow (BM) significantly promotes new bone formation in rabbits. This combination shows potential as an ideal bone substitute for future clinical applications.

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Skeletal Biology

Context:

  • Bone defects and loss represent significant clinical challenges.
  • Autografts and allografts have limitations, driving the search for effective bone substitutes.
  • Ceramic-like xenogeneic bone (CXB) is a potential candidate for bone regeneration.

Purpose:

  • To evaluate the osteogenic potential of ceramic-like xenogeneic bone (CXB) when combined with bone marrow (BM).
  • To compare the osteogenesis of CXB with BM against CXB alone in a rabbit model.

Summary:

  • CXB combined with BM was implanted into rabbit sacrospinalis muscles.
  • Histological and histochemical analyses were performed at various time points (2-24 weeks).
  • Significant cartilage and new bone formation, including medullary cavity development, were observed with CXB + BM, while CXB alone showed no osteogenesis.

Related Experiment Videos

Impact:

  • CXB combined with BM demonstrates osteoconductive and osteoinductive properties.
  • The combination supports the formation of osteoblasts and chondroblasts, crucial for bone healing.
  • This study suggests CXB + BM is a promising bone substitute with potential for future clinical translation.