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Published on: September 11, 2015
[The experimental study of membrane-guided tissue regeneration of bone]
1Department of Plastic Surgery, General Hospital of Guang zhou Military Region, Guangzhou, Guangdong, P. R. China 510010.
Objective:
To confirm membrane-guided tissue regeneration in the healing course of segmental bone defects and study the mechanism.
Methods:
Segmental, 1 cm osteoperiosteal defects were produced in both radii of 12 rabbits. One side was covered with hydroxyapatite/polylactic acid(HA/PLA) membrane encapsulated as a tube. The contralateral side served as an untreated control. Healing courses were detected by radiographic and histologic examinations.
Results:
All control sides showed nonunion, whereas there were consistent healing pattern in test sides.
Conclusion:
Membrane technique can promote bone regeneration.
