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Minute pulmonary meningothelial-like nodules: high-resolution computed tomography and pathologic correlations
Masaomi Kuroki1, Hiroshi Nakata, Toshifumi Masuda
1Department of Radiology, Miyazaki Medical College, Kiyotake, Japan. mkuroki@post1.miyazaki-med.ac.jp
Journal of Thoracic Imaging
|June 26, 2002
Summary
Minute pulmonary meningothelial-like nodules (MPMNs) are rare lung lesions. This case highlights their association with lung adenocarcinoma, visible as tiny ground-glass nodules on HRCT.
Area of Science:
- Pulmonary pathology and radiology
Background:
- Minute pulmonary meningothelial-like nodules (MPMNs), formerly minute pulmonary chemodectomas, are uncommon interstitial lung lesions.
- MPMNs are characterized by nodular proliferation of cells in a "zellenballen" pattern and are associated with conditions like thromboembolism, cardiac disease, and malignancy.
Observation:
- A case of MPMNs co-occurring with adenocarcinoma of the lung is presented.
- High-resolution computed tomography (HRCT) revealed tiny (1-3 mm) ground-glass attenuation nodules.
Findings:
- The study describes the pathological and radiological features of MPMNs in a patient with lung adenocarcinoma.
- MPMNs present as small, often multiple, interstitial nodules.
Implications:
- This case underscores the importance of considering MPMNs in the differential diagnosis of small lung nodules, especially in patients with known malignancy.
- Further research into the origin and function of MPMN cells may clarify their role in lung pathology.