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Updated: Sep 30, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
Published on: April 28, 2016
[Ghrelin--peptide hormone that increases appetite. It opens new possibilities for the research on energy metabolism]
1Biocenter Oulu, Uleåborgs universitet, Kajaanintie 50/PB 5000, FIN-900 14 Uleåborg, Finland. olavi.ukkola@oulu.fi
Abstract:
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHS-R) that potently stimulates growth hormone (GH) release. The discovery of ghrelin opens up a new regulatory system for GH secretion. Surprisingly, recent studies in rodents suggest that peripherally or centrally administered ghrelin, independent of GH, decreases fat oxidation and increases food intake and adiposity. In addition, plasma ghrelin levels are lower in obese human subjects. Ghrelin might participate in meal initiation and may signal to the hypothalamus when an increase in metabolic efficiency is needed.
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