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Structural mimicry of proline kinks: tertiary packing interactions support local structural distortions

Marc A Ceruso1, Harel Weinstein

  • 1Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, NY 10029-6574, USA.

Journal of Molecular Biology
|June 27, 2002
PubMed
Summary

Protein structural distortions, known as proline-kinks, can occur without proline residues. Differential packing interactions between helical segments are the key mechanism stabilizing these features.

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