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Hormonal therapies in acne.

James C Shaw1

  • 1Division of Dermatology, Toronto Western Hospital, East Wing 8-517, 399 Bathurst Street, Toronto, Ontario, M5T 2S8, Canada. jc.shaw@utoronto.ca

Expert Opinion on Pharmacotherapy
|June 27, 2002
PubMed
Summary

Hormonal therapies are effective for treating acne, particularly in adult women. This review explores the science behind hormonal acne treatments and future therapeutic options.

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Area of Science:

  • Dermatology and Endocrinology

Background:

  • Androgen hormones are a primary cause of acne across all age groups.
  • Hormonal therapies offer a rational and effective approach to acne management.

Purpose of the Study:

  • To review the physiological basis of hormonal influence on acne.
  • To discuss current and emerging hormonal acne treatments.

Main Methods:

  • Review of scientific literature on hormonal acne.
  • Analysis of current and investigational hormonal therapies.

Main Results:

  • Hormonal treatments, especially for women with persistent acne, are well-established.
  • Key treatments include oral contraceptives, androgen receptor blockers (e.g., spironolactone), 5 alpha-reductase inhibitors, and topical hormonal agents.

Conclusions:

  • Hormonal therapies remain a cornerstone in acne treatment, particularly for specific patient populations.
  • Future research holds promise for novel hormonal interventions in acne management.

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