Related Experiment Video
Updated: Aug 14, 2026

Precision Implementation of Minimal Erythema Dose (MED) Testing to Assess Individual Variation in Human Inflammatory Response
Published on: October 3, 2019
Contact urticaria due to polyethylene gloves
Keiji Sugiura1, Mariko Sugiura, Rika Shiraki
1Department of Environmental Dermatology, Nagoya University School of Medicine, Nagoya, Japan.
Abstract:
We report a rare case of contact urticaria due to polyethylene gloves. The patient, a 46-year-old cook, had had had chronic urticaria since 1985, and first visited our hospital in June 2000. We began by prescribing antihistamine and antiallergenic drugs for him, but his condition did not improve. From a detailed interview, we established that when he put on polyethylene gloves at work, his condition worsened. We suspected some component of his gloves to be the cause of his symptoms. Prick and scratch tests with a solution extracted from his gloves showed a wheal-and-flare reaction at 15 min. We advised him to wear a cotton shirt under his clothes in daily life, and to put on cotton gloves under his polyethylene gloves while at work. Subsequently, the size and the number of wheals were markedly smaller and the subject's symptoms were reduced.
Related Concept Videos
Allergic Reactions
Hand hygiene
Hand washing...
Personal Protective Equipment
PPE Use in Healthcare Settings I: Donning
PPE Use in Healthcare Settings II: Doffing
Handwashing III: During the Procedure and Post-Procedure Steps

