Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nephron-sparing surgery.

R Ghavamian1, H Zincke

  • 1Albert Einstein College of Medicine, Montefiore Medical Center, 34 Bainbridge Avenue, 5th Floor, Bronx, NY 10467, USA. rdhavami@montefiore.org

Current Urology Reports
|June 27, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Carcinoma in Situ of the Bladder.

Cancer·2018
Same author

Comparison of Dimensional Accuracy between Open-Tray and Closed-Tray Implant Impression Technique in 15° Angled Implants.

Journal of dentistry (Shiraz, Iran)·2014
Same author

Bilateral renal-cell cancer treated surgically is associated with favorable disease outcome.

International journal of oncology·2011
Same author

Urothelial carcinoma of the bladder with choriocarcinomatous differentiation A report of two cases and review of the literature.

Urologic oncology·2011
Same author

Renal insufficiency is an independent risk factor for complications after partial nephrectomy.

The Journal of urology·2009
Same author

Prediction of site-specific metastases in surgically treated nonmetastatic renal cell cancer. Changes of follow-up protocol.

Der Urologe. Ausg. A·2004
Same journal

Effective Mentorship in Urology Fellowship Training: Qualities, Models, and Equity.

Current urology reports·2026
Same journal

Management of Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis.

Current urology reports·2026
Same journal

Lower Urinary Tract Symptoms as an Indicator of Occult Neurologic Disease: A System-first Framework for Urologic Practice.

Current urology reports·2026
Same journal

Association Between Ambient Temperature and Urolithiasis: A Systematic Review and Meta-analysis.

Current urology reports·2026
Same journal

Is Open Partial Nephrectomy Still an Option in the Robotic Era?

Current urology reports·2026
Same journal

Artificial Intelligence in Urologic Documentation: A Review of Emerging Capabilities and the Ongoing Need for Human Oversight.

Current urology reports·2026
See all related articles

Nephron-sparing surgery (NSS) is increasingly justified for localized renal cell carcinoma, offering equivalent curative outcomes to radical nephrectomy, especially for smaller tumors.

Area of Science:

  • Urology
  • Surgical Oncology
  • Nephrology

Background:

  • Renal cell carcinoma (RCC) management is primarily surgical.
  • Advances in imaging increase detection of incidental RCCs.
  • Radical nephrectomy is often the standard for localized RCC with a healthy contralateral kidney.

Purpose of the Study:

  • To evaluate the evolving indications for nephron-sparing surgery (NSS) in renal cell carcinoma.
  • To compare the efficacy of NSS versus radical nephrectomy for localized RCC.
  • To highlight factors supporting NSS as a viable alternative.

Main Methods:

  • Review of recent data and surgical techniques.
  • Analysis of studies on RCC biology and multifocality.
  • Consideration of earlier diagnostic trends.

Related Experiment Videos

Main Results:

  • Radical nephrectomy and NSS provide equivalent curative treatment for most renal cell carcinomas, particularly those ≤ 4 cm.
  • Growing evidence supports NSS in select patients even with a normal contralateral kidney.
  • Indications for NSS have expanded over the last decade.

Conclusions:

  • Nephron-sparing surgery is an increasingly attractive option for urologists managing renal cell carcinoma.
  • Refined surgical techniques and a better understanding of RCC biology support the expanded use of NSS.
  • NSS offers a justifiable alternative to radical nephrectomy in appropriate clinical scenarios.