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Access-related complications in peritoneal dialysis in developing countries
Narayan Prasad1, Amit Gupta, Milly Mathew
1Department of Nephrology, SGPIMS, Lucknow, India.
Summary
Access complications in peritoneal dialysis vary between acute and chronic cases due to differences in catheter design and duration. Pain is the most common acute complication, while exit-site infections are more prevalent in chronic cases.
Area of Science:
- Nephrology
- Medical Devices
- Patient Care
Background:
- Access-related complications are a significant concern in peritoneal dialysis (PD).
- Differences in PD type (acute vs. chronic) influence complication profiles.
- Catheter design, material, and PD duration are key influencing factors.
Purpose of the Study:
- To compare access-related complications between acute and chronic peritoneal dialysis.
- To identify the incidence and types of complications specific to each PD modality.
- To highlight variations in exit-site care practices.
Main Methods:
- Retrospective analysis of complication data from acute and chronic PD patients.
- Review of literature on PD access complications.
- Comparison of complication rates based on PD type and influencing factors.
Main Results:
- Acute PD: Pain (56-75%), bloody effluent (30%), pericatheter leak (14-36%), catheter malfunction (12-28%), bowel injury (0.1-1.3%), peritonitis (2.5%).
- Chronic PD: Exit-site infections (1 per 27.3-41.9 patient-months), pericatheter leak (5.2%).
- Significant differences in complication incidence and type observed between acute and chronic PD.
Conclusions:
- Acute and chronic PD present distinct access complication profiles.
- Catheter characteristics and PD duration significantly impact complication rates.
- Standardized exit-site care protocols, including mupirocin use, may help reduce infections in chronic PD.