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Analysis of facial growth in subjects with syndromic ectodermal dysplasia: a longitudinal analysis
N Bondarets1, R M Jones, F McDonald
1Department of Orthodontics, Institute for Advanced Dental Education, Ministry of Public Health, Moscow, Russia.
Objective:
To examine the craniofacial growth pattern of patients diagnosed with syndromic ectodermal dysplasia.
Design:
Mixed longitudinal analysis of lateral cephalograms.
Setting:
The data were analysed using a multilevel modelling technique with the MLwiN application software and the results presented numerically and graphically.
Sample Population:
All 61 subjects had severe hypodontia with the number of absent teeth (excluding third molars) ranging from 6 to 28 (mean = 15.4). At presentation the subjects had a mean age of 133 months and were followed longitudinally for between one and five subsequent occasions (mean 2.66 occasions; mean age at completion of observation 207 months).
Outcome Measures:
Lateral cephalograms taken at each visit.
Experimental Variables:
Analysis of four angular measurements and four linear measurements, together with one calculated ratio.
Results:
Growth curves are presented showing the trends of craniofacial growth.
Conclusions:
The most significant findings were for a universal tendency for the individuals to undergo a change in sagittal relationship of the jaws, becoming markedly more Class III with time. We have also demonstrated a significant difference in growth between the anterior and posterior face heights indicating that the subjects have a tendency to an anterior growth rotation.