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[A checking system for injectable anticancer drugs using each patient's own data and its evaluation].

Yasuaki Ohtsubo1, Keizo Ishimito, Momoe Tanioka

  • 1Department of Pharmacy, Yamaguchi University Hospital, 1-1-1 Minamikogushi, Ube 755-8505, Japan. bookston-ygc@umin.ac.jp

Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|June 29, 2002
PubMed
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A new system enhances injectable anticancer drug safety by providing real-time prescription checks and automated preparation calculations. This risk management tool significantly reduces medication errors and preparation time for pharmacists.

Area of Science:

  • Oncology
  • Pharmacology
  • Health Informatics

Context:

  • Injectable anticancer drug use presents complex challenges in dosage and administration.
  • Pharmacists face difficulties in verifying prescriptions and ensuring aseptic intravenous (IV) admixing.
  • Existing methods are time-consuming and prone to errors.

Purpose:

  • To develop and evaluate a checking system for risk management of injectable anticancer drug use.
  • To provide real-time verification of dosage, infusion rates, and dosing schedules.
  • To streamline the aseptic IV admixing process and enhance patient safety.

Summary:

  • The system performs real-time checks using patient-specific data (height, weight, BSA, medical history, ICD10 code) and drug information.
  • It automatically calculates liquid volumes for admixing, lists stability times, and incorporates clinical laboratory results.

Related Experiment Videos

  • The system identified 24 medication errors and 13 contraindications before administration in its first six months.
  • Impact:

    • Prevented medication errors including incorrect doses and inappropriate dosing intervals.
    • Reduced aseptic IV admixing preparation time by 73%.
    • Enabled advance identification of patients for whom the drug is contraindicated, improving rational drug use and risk management.