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Possible genotoxic activity of extracts of Bryonia alba roots on human lymphocytes and transformed cells
1Laboratory of Carcinogenesis, Cancer Research Center, Yerevan, Armenia. genetik@ysu.am
Abstract:
Bryonia alba roots (BAR) are widely used as an adaptogenic and restorative drug with immunomodulatory and stress-protective properties that increase the non-specific resistance of an organism toward harmful stimuli. Potential genotoxic activity of aqueous and methanol extracts of BAR was studied on human normal (lymphocytes) and transformed (HeLa and Caco-2) cells using single cell gel electrophoresis (the comet assay). The results obtained did not show any evidence of genotoxic effects of BAR.
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