Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ageing, hormones, body composition, metabolic effects.

Alex Vermeulen1

  • 1Section of Endocrinology, Medical Clinic, University Hospital, De Pintelaan, Belgium. alex_vermeulen@hotmail.com

World Journal of Urology
|June 29, 2002
PubMed
Summary

Aging leads to decreased testosterone (T) and growth hormone (GH) levels, impacting body composition. Hormone therapy may help reverse age-related muscle loss and fat gain, suggesting hormones are key factors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global nature run data with realistic high-resolution carbon weather for the year of the Paris Agreement.

Scientific data·2022
Same author

A historical, geographical and ecological perspective on the 2018 European summer drought.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2020
Same author

Iconic CO2 time series at risk.

Science (New York, N.Y.)·2012
Same author

The epidemic of obesity: obesity and health of the aging male.

The aging male : the official journal of the International Society for the Study of the Aging Male·2005
Same author

The decline of androgen levels in elderly men and its clinical and therapeutic implications.

Endocrine reviews·2005
Same author

Monitoring and modelling of biosphere/atmosphere exchange of gases and aerosols in Europe.

Environmental pollution (Barking, Essex : 1987)·2004

Area of Science:

  • Endocrinology
  • Gerontology
  • Body Composition Research

Background:

  • Aging is associated with significant body composition changes, including muscle mass decline, fat mass increase, and reduced bone mineral density.
  • These changes mirror those seen in hypogonadism and hyposomatotropism, suggesting a hormonal link.
  • Age-related body composition shifts have profound functional and metabolic consequences.

Purpose of the Study:

  • To explore the relationship between age-associated changes in hormone levels (testosterone and growth hormone) and body composition.
  • To investigate the potential causal role of hormones in these age-related alterations.
  • To assess the impact of hormone substitution therapy on age-related body composition changes.

Main Methods:

  • Correlation analysis between plasma hormone levels (testosterone, growth hormone) and body composition parameters (muscle mass, fat mass, bone mineral density).
  • Comparative analysis of age-associated changes with conditions like hypogonadism and hyposomatotropism.
  • Review of studies on hormone substitution therapy effects on body composition.

Main Results:

  • Significant positive correlations observed between muscle mass and bone mineral density with testosterone (T) and growth hormone (GH) levels.
  • Negative correlations found between abdominal fat mass and T and GH levels.
  • Hormone substitution therapy demonstrated beneficial effects on body composition.

Conclusions:

  • Testosterone and growth hormone levels are closely linked to age-associated body composition changes.
  • While the causal relationship is debated, hormones appear to be co-determinants of these alterations.
  • Hormone therapy suggests a potential therapeutic avenue for mitigating age-related body composition decline.

Related Experiment Videos