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Posttrabeculectomy endophthalmitis caused by Moraxella nonliquefaciens
Helene Laukeland1, Kåre Bergh, Lars Bevanger
1Department of Ophthalmology, University Hospital and Department of Laboratory Medicine, Norwegian University of Science and Technology, N-7006 Trondheim, Norway.
Journal of Clinical Microbiology
|June 29, 2002
Summary
Moraxella nonliquefaciens, a common upper respiratory organism, can cause severe endophthalmitis years after glaucoma surgery. This finding highlights the need for vigilance in identifying this pathogen in post-surgical eye infections.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Moraxella nonliquefaciens is a commensal bacterium of the upper respiratory tract.
- It is generally regarded as having low pathogenic potential.
Observation:
- Two cases of severe endophthalmitis are presented.
- These infections occurred 9 years and 2 months post-glaucoma filtration surgery.
Findings:
- Bacterial identification was confirmed using phenotypic characteristics and 16S rRNA gene sequencing.
- Moraxella nonliquefaciens demonstrated very low minimum inhibitory concentrations (MICs) for several tested antibiotics, except sulfonamide.
Implications:
- This study expands the known clinical spectrum of Moraxella nonliquefaciens infections.
- It underscores the potential for delayed, severe ocular infections by this organism following intraocular surgery.
- Further research into the pathogenicity and treatment of Moraxella nonliquefaciens endophthalmitis is warranted.