[Programmed cell death in the pathogenesis of human diseases]

The distempers considering cell dying have an important meaning in pathogenesis of different diseases, just like the proliferation distempers. Proliferation and dying are probably responsible for homeostasis support at the same part. Two groups of distempers were distinguished. One of them is connected with an increased cell viability (some cancers, autoimmunological diseases, viral infections) and the other where there is an increased cell mortality (AIDS, some neurodegenerative diseases, myelodysplastic syndromes, osteoporosis and others). Programmed cell death induction using gene therapy methods is tested in preclinical examinations. The results of these tests are thought to have an important significance in therapy of many diseases.