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[Effects of peripheral functional electrostimulation in obstructive bladder instability]
F García Montes1, A R Mundy, S Knight
1Hospital Universitario Son Dureta, Palma de Mallorca, Baleares, España.
Actas Urologicas Espanolas
|July 2, 2002
Summary
Functional electrical stimulation (FES) did not significantly reduce unstable bladder contractions in men with detrusor instability (DI) due to benign prostatic hyperplasia (BPH). This suggests DI in BPH may stem from peripheral issues, not sacral reflexes.
Area of Science:
- Urology
- Neuroscience
- Physiology
Context:
- Detrusor instability (DI) is a common condition.
- Obstructive benign prostatic hyperplasia (BPH) frequently causes secondary DI.
- Current treatments for DI secondary to BPH have limitations.
Purpose:
- To evaluate the efficacy of peripheral functional electrical stimulation (FES) in managing DI secondary to BPH.
- To determine if FES can suppress involuntary detrusor contractions.
- To explore the underlying pathophysiology of DI in BPH.
Summary:
- Nine patients with urodynamically confirmed DI secondary to BPH were studied.
- Individually optimized FES was applied during unstable detrusor contractions.
- FES resulted in less than 10% suppression of unstable contractions, with no statistically significant difference compared to controls.
Impact:
- Peripheral FES does not appear to be an effective treatment for DI secondary to BPH.
- The findings suggest that DI in this population may have a peripheral pathophysiological origin (myogenic and/or nerve endings).
- This supports the hypothesis that sacral reflex mechanisms are not the primary drivers of obstructive DI in BPH.