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Monitoring cardiovascular function in infants with chronic lung disease of prematurity

S H Abman1

  • 1Department of Pediatrics, B-395, The Children's Hospital, 1056 E, Denver, CO 80218, USA. steve.abman@uchsc.edu

Archives of Disease in Childhood. Fetal and Neonatal Edition
|July 2, 2002
PubMed

Insights

Premature birth survivors with chronic lung disease face cardiovascular risks like pulmonary hypertension. Treatments include oxygen, medications, and potentially inhaled nitric oxide for long-term management.

Area of Science:

  • Neonatal medicine
  • Cardiology
  • Pulmonology

Background:

  • Premature birth survivors with chronic lung disease (CLD) are susceptible to significant cardiovascular complications.
  • These sequelae include pulmonary hypertension, systemic hypertension, left ventricular hypertrophy, and exercise intolerance.

Purpose of the Study:

  • To outline the cardiovascular risks associated with chronic lung disease in premature infants.
  • To discuss current and emerging treatment strategies for these conditions.

Main Methods:

  • Review of existing literature on cardiovascular outcomes in premature infants with CLD.
  • Analysis of treatment guidelines and ongoing research for pulmonary hypertension management.

Main Results:

  • Pulmonary hypertension is a primary concern, often managed with supplemental oxygen.
  • Pharmacological interventions like calcium channel blockers may be necessary.
  • Inhaled nitric oxide is under investigation for long-term management of pulmonary hypertension.

Conclusions:

  • Cardiovascular health is a critical concern for premature infants with CLD.
  • A multi-faceted treatment approach is required, including oxygen, medication, and novel therapies.
  • Further research into inhaled nitric oxide is warranted for improved long-term outcomes.

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