[CA 15-3 and CEA markers - prognostic factors in breast cancer]

For the increasing of sensibility and specificity in the monitoring of the diagnosis and treatment of breast cancer it is used the simultaneous determination of two tumoral markers: CA 15-3 and CEA. This study try to demonstrate the grade of involvement in diagnostic and screening. We have determinate CA 15-3 and CEA in 73 serum samples. The correlation between the stage of malignancies and CA 15-3 levels was relieved in the second section of this study. The third section follow up the dynamic evolution of CA 15-3 marker in pre- and postoperator (14 days) stages obtaining a decreasing of CA 15-3 level. The obtained results for CEA does not establish any clinical rules in order to compare with the CA 15-3 level and disease stages. The easy-used and non-invasive determination, the early increasing of it's level and it's preservation recommend glycoprotein CA 15-3 like an current clinical instrument.