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[Locally advanced breast cancer in the elderly]
1Disciplina de Oncologie-Radioterapie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Summary
Older women with locally advanced breast cancer can safely undergo radical surgery and adjuvant chemohormonotherapy. Treatment decisions should consider clinical stage and pathology for optimal outcomes in elderly patients.
Area of Science:
- Oncology
- Geriatric Medicine
- Surgical Oncology
Context:
- Limited data exists on breast cancer treatment for elderly patients with locally advanced disease.
- Focus on women aged 65 and older with locally advanced breast cancer.
- Investigating the impact of age on treatment efficacy and patient outcomes.
Purpose:
- To determine if treatment modalities influence outcomes in older women with locally advanced breast cancer.
- To assess the effect of clinical stage and pathological type on treatment success.
- To evaluate the safety and feasibility of aggressive treatment regimens in the elderly population.
Summary:
- Review of treatment strategies for locally advanced breast cancer in women over 65.
- Radical surgical procedures are recommended for patients without metastatic disease.
- Loco-regional therapy combined with adjuvant chemohormonotherapy is safe and feasible for older patients.
Impact:
- Provides evidence supporting aggressive treatment for elderly patients with locally advanced breast cancer.
- Highlights the importance of considering individual patient factors like stage and pathology.
- Informs clinical decision-making for optimizing breast cancer care in geriatric populations.