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[Neurogenetics in Parkinson's disease]
F Stefanache1, D Hodorog, D Cuciureanu
1Facultatea de Medicină, Clinica I Neurologie, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Abstract:
The pathogenesis of Parkinson's disease, a progressive degenerative disorder of the central nervous system, remains obscure. 20% of cases are familial. The disorder may be due to a combination of genetic and environmental factors. Some monogenic forms of Parkinson's disease have been described. Many genetic studies explore whether a candidate gene may confer an increased risk for this disease. The search for a genetic susceptibility may lead to establish a preventive therapy.