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[Nebivolol treatment in essential arterial hypertension]
1Facultatea de Medicină Clinica a III-a Medicală I. Enescu, Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi.
Abstract:
Nebivolol is a lipophilic beta 1-blocker. It is devoid of intrinsic sympathomimetic or membrane stabilising activity but appears to have nitric oxide-mediated vasodilatory effects. Nebivolol 5 mg once daily is well tolerated in patients with hypertension. Adverse events are infrequent, transient and mild to moderate. Those reported most often include headache, fatigue, paraesthesias and dizziness. Several studies reported no signs of orthostatic hypotension with Nebivolol.