Related Experiment Video
Updated: Aug 9, 2026

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
Published on: December 28, 2021
Relaxation degree: a new concept in erectile dysfunction
Purpose:
To investigate the clinical application of the new parameter' Relaxation Degree.
Patients And Methods:
Chart reviews of 150 patients were evaluated retrospectively of whom 96 had been diagnosed as pure cavernoocclusive dysfunction (COD) by using corpus cavernosum electromyography (CC-EMG) and cavernosometry and of whom 54 had been diagnosed as psychogenic erectile dysfunction by normal CC-EMG; cavernosometry and pulse doppler scanning. Relaxation degree was defined as the percent decrease in the amplitudes of the electrical activity of corpus cavernosum (EACC).
Results:
Mean relaxation degree measurements were found as 66.5%, 66.28% and 16% in minimal, moderate and severe COD groups respectively. This value was 80% in psychogenic erectile dysfunction group. Statistical comparisons were found significant between minimal and severe and moderate and severe COD groups. All three organic erectile dysfunction groups were also compared with psychogenic erectile dysfunction group where differences were found significant. If the normal relaxation degree was accepted as more than 80%, COD could be diagnosed with 93% specificity and 98% sensitivity without performing cavernosometry.
Conclusion:
Relaxation degree parameter could be used in diagnosis of COD showing the percent relaxation ability of the cavernous smooth muscle as a non invasive method when compared with cavernosometry.
Related Concept Videos
Nitric Oxide Signaling Pathway
Peripherally and Centrally Acting Muscle Relaxants: A Comparison
Centrally acting muscle relaxants can be further divided into spasmolytic and antispasmodic drugs. Spasmolytic drugs,...
Relaxation of Skeletal Muscles
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open.
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Male Sexual Response: Erection & Ejaculation
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

