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Interrupted Aortic Arch.

Satinder K. Sandhu1, Timothy W. Pettitt

  • 1Pediatric Cardiology, Louisiana State University Medical Center, Children's Hospital, 200 Henry Clay Avenue, New Orleans, LA 70118, USA. ssandh@lsuhsc.edu

Current Treatment Options in Cardiovascular Medicine
|July 3, 2002
PubMed
Summary

Interruption of the aortic arch is a rare congenital heart defect where the aorta lacks continuous flow. This condition often accompanies other cardiac abnormalities, affecting approximately 1% of patients with congenital heart disease.

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Area of Science:

  • Cardiology
  • Developmental Biology
  • Medical Malformations

Background:

  • Interruption of the aortic arch (IAA) is a severe congenital heart defect characterized by a lack of luminal continuity between the ascending and descending aorta.
  • This malformation is rarely an isolated finding and frequently co-occurs with other significant cardiac anomalies.

Purpose of the Study:

  • To define Interruption of the Aortic Arch (IAA).
  • To highlight the common co-occurrence of IAA with other congenital heart defects.
  • To state the prevalence of IAA in patients with congenital heart defects.

Main Methods:

  • Literature review of congenital heart defect classifications.
  • Analysis of epidemiological data on congenital heart malformations.

Main Results:

  • Interruption of the aortic arch is defined by the absence of aortic luminal continuity.
  • Common associated defects include ventricular septal defect and patent ductus arteriosus.
  • IAA occurs in approximately 1% of individuals diagnosed with congenital heart defects.

Conclusions:

  • Interruption of the aortic arch is a rare but serious congenital heart malformation.
  • Its frequent association with other cardiac defects underscores the complexity of aortic arch development.
  • Understanding the prevalence and associated defects is crucial for diagnosis and management.

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