Adefovir nephrotoxicity and mitochondrial DNA depletion

Polymerization of the triphosphates of AraC, 2',2'-difluorodeoxycytidine (dFdC) and OSI-7836 (T-araC) by human DNA polymerase alpha and DNA primase.

Biochemical pharmacology·2004

Mice deficient for cytosolic thymidine kinase gene develop fatal kidney disease.

Molecular genetics and metabolism·2003

Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.

Chemical research in toxicology·2002

Neoadjuvant chemotherapy remodels the three-dimensional vascular architecture and immune microenvironment in pancreatic ductal adenocarcinoma.

Human pathology·2026

Duct Quest: An International Survey of Genitourinary and Community Pathologists Reveals Diagnostic Uncertainties in Separating Atypical Intraductal Proliferation from High-grade Prostatic Intraepithelial Neoplasia and Intraductal Carcinoma of the Prostate.

Human pathology·2026

HER2 status in extrahepatic cholangiocarcinoma and gallbladder carcinoma: concordance between immunohistochemistry and chromogenic in situ hybridization in 140 Cases.

Human pathology·2026

Histopathological differences between idiopathic and secondary interstitial pneumonia: An elastic fiber-oriented deep learning analysis.

Human pathology·2026

Non-small cell lung carcinomas with diffuse co-expression of TTF-1 and p40: clinicopathologic and molecular characterization of a rare phenotype.

Human pathology·2026

Myeloid sarcoma: Clinical, Pathologic, and Molecular Findings.

Human pathology·2026

Hepatitis Overview: Less Common Causes of Hepatitis.

FP essentials·2026

Hepatitis Overview: Viral Hepatitis.

FP essentials·2026

Finerenone and apparent treatment-resistant hypertension in heart failure with mildly reduced or preserved ejection fraction.

European journal of heart failure·2026

Large Pericardial Effusion as a Manifestation of Overlapping Hydralazine-Induced Lupus and ANCA Vasculitis.

JACC. Case reports·2026

Hypotension Prediction Index versus High Mean Arterial Pressure Target for Preventing Intraoperative Hypotension: A Randomized Controlled Trial.

Anesthesiology·2026

Integrative Transcriptomics Links Dapagliflozin-Opposed Macrophage Programs to BHLHE40-Associated Regulation and NFKB1-Associated Signaling in HFpEF.

Omics : a journal of integrative biology·2026

Related Experiment Videos

Adefovir nephrotoxicity and mitochondrial DNA depletion

Related Concept Videos

Polymerization of the triphosphates of AraC, 2',2'-difluorodeoxycytidine (dFdC) and OSI-7836 (T-araC) by human DNA polymerase alpha and DNA primase.

Mice deficient for cytosolic thymidine kinase gene develop fatal kidney disease.

Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.

Neoadjuvant chemotherapy remodels the three-dimensional vascular architecture and immune microenvironment in pancreatic ductal adenocarcinoma.

Duct Quest: An International Survey of Genitourinary and Community Pathologists Reveals Diagnostic Uncertainties in Separating Atypical Intraductal Proliferation from High-grade Prostatic Intraepithelial Neoplasia and Intraductal Carcinoma of the Prostate.

HER2 status in extrahepatic cholangiocarcinoma and gallbladder carcinoma: concordance between immunohistochemistry and chromogenic in situ hybridization in 140 Cases.

Histopathological differences between idiopathic and secondary interstitial pneumonia: An elastic fiber-oriented deep learning analysis.

Non-small cell lung carcinomas with diffuse co-expression of TTF-1 and p40: clinicopathologic and molecular characterization of a rare phenotype.

Myeloid sarcoma: Clinical, Pathologic, and Molecular Findings.

Hepatitis Overview: Less Common Causes of Hepatitis.

Hepatitis Overview: Viral Hepatitis.

Finerenone and apparent treatment-resistant hypertension in heart failure with mildly reduced or preserved ejection fraction.

Large Pericardial Effusion as a Manifestation of Overlapping Hydralazine-Induced Lupus and ANCA Vasculitis.

Hypotension Prediction Index versus High Mean Arterial Pressure Target for Preventing Intraoperative Hypotension: A Randomized Controlled Trial.

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Adefovir nephrotoxicity and mitochondrial DNA depletion

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