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Preventing mother-to-child HIV transmission: the first year of Thailand's national program
Pornsinee Amornwichet1, Achara Teeraratkul, R J Simonds
1Department of Health, Ministry of Public Health, Tivanon Road, Nonthaburi, 11000, Thailand.
Insights
Thailand
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- Global Health
Background:
- Thailand implemented a national program in 2000 to prevent mother-to-child HIV transmission.
- Approximately 10,000 children annually are born at risk in Thailand.
Purpose of the Study:
- To evaluate the implementation and outcomes of Thailand's national program for preventing mother-to-child HIV transmission.
Main Methods:
- Data collected monthly from 822 public health hospitals across 12 regions.
- Study included women giving birth between October 2000 and September 2001 and their neonates.
- Key outcomes measured were HIV testing rates, antenatal antiretroviral prophylaxis for mothers, and neonatal antiretroviral prophylaxis and infant formula.
Main Results:
- Over 96% of women received antenatal care, with 93.3% tested for HIV.
- 70.1% of HIV-seropositive women received prophylactic antiretroviral drugs before delivery.
- 88.7% of exposed neonates received antiretroviral drugs and 83.2% received infant formula.
Conclusions:
- Thailand's national program successfully implemented key components for preventing mother-to-child HIV transmission.
- The program's success offers a model for other developing countries to consider for similar initiatives.
Context:
Each year in Thailand, about 10,000 children are born at risk for mother-to-child human immunodeficiency virus (HIV) transmission. In 2000, Thailand implemented a national program to prevent mother-to-child HIV transmission.
Objective:
To describe the results of implementation of the program.
Design:
Monthly collection of summary data from hospitals.
Setting:
Public health hospitals (n = 822) in all 12 regions of Thailand, representing 75 provinces, excluding Bangkok.
Participants:
Women giving birth from October 2000 through September 2001, including HIV-seropositive women and their neonates.
Main Outcome Measures:
Percentages of women giving birth who were tested for HIV, HIV-seropositive women giving birth who received antenatal prophylactic antiretroviral drugs, and HIV-exposed neonates who received prophylactic antiretroviral drugs and infant formula.
Results:
Among 573,655 women (range, 27,344-77,806 by region) giving birth, 554,912 (96.7%) received antenatal care (range, 91.9%-98.8% by region). Of 554,912 women giving birth who had antenatal care, 517,488 (93.3%) were tested for HIV (range, 87.7%-99.4% by region) before giving birth; of 18,743 women giving birth who did not have antenatal care, 13,314 (71.0%) were tested for HIV (range, 21.7%-92.9% by region). Of 6646 HIV-seropositive women giving birth, 4659 (70.1%) received prophylactic antiretroviral drugs before delivery (range, 55.3%-81.2% by region). Of 6475 neonates of HIV-seropositive women, 5741 (88.7%) received prophylactic antiretroviral drugs (range, 67.4%-96.9% by region) and 5386 (83.2%) received infant formula (range, 65.3%-100% by region).
Conclusions:
Major program components of Thailand's national program for preventing mother-to-child HIV transmission were implemented. Thailand's experience may encourage other developing countries to implement or expand similar national programs.
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