Preventing mother-to-child HIV transmission: the first year of Thailand's national program

Pornsinee Amornwichet1, Achara Teeraratkul, R J Simonds

  • 1Department of Health, Ministry of Public Health, Tivanon Road, Nonthaburi, 11000, Thailand.

JAMA
|July 4, 2002
PubMed

Insights

Thailand

Area of Science:

  • Public Health
  • Infectious Disease Epidemiology
  • Global Health

Background:

  • Thailand implemented a national program in 2000 to prevent mother-to-child HIV transmission.
  • Approximately 10,000 children annually are born at risk in Thailand.

Purpose of the Study:

  • To evaluate the implementation and outcomes of Thailand's national program for preventing mother-to-child HIV transmission.

Main Methods:

  • Data collected monthly from 822 public health hospitals across 12 regions.
  • Study included women giving birth between October 2000 and September 2001 and their neonates.
  • Key outcomes measured were HIV testing rates, antenatal antiretroviral prophylaxis for mothers, and neonatal antiretroviral prophylaxis and infant formula.

Main Results:

  • Over 96% of women received antenatal care, with 93.3% tested for HIV.
  • 70.1% of HIV-seropositive women received prophylactic antiretroviral drugs before delivery.
  • 88.7% of exposed neonates received antiretroviral drugs and 83.2% received infant formula.

Conclusions:

  • Thailand's national program successfully implemented key components for preventing mother-to-child HIV transmission.
  • The program's success offers a model for other developing countries to consider for similar initiatives.
Abstract

Related Concept Videos

Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Primary Healthcare Services01:30

Primary Healthcare Services

Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
Levels of Health Promotion and Illness Prevention01:26

Levels of Health Promotion and Illness Prevention

Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...