Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comparative cardiovascular development: improving the conceptual framework.

Warren Burggren1, Dane A Crossley

  • 1Department of Biological Sciences, University of North Texas, Denton 76205, USA. burggren@unt.edu

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
|July 4, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating effects of acute severe hypoxia and p38 MAPK inhibition on boldness and anxiety-like behavior in zebrafish larvae.

Frontiers in behavioral neuroscience·2026
Same author

Embryonic hypoxia alters cardiac gene expression patterns in American alligators, Alligator mississippiensis.

Physiological genomics·2025
Same author

The impact of adult and lifelong hypoxia on ventricle phenotype in zebrafish (<i>Danio rerio</i>).

American journal of physiology. Regulatory, integrative and comparative physiology·2025
Same author

Strain-Specific developmental cardiovascular physiology landmarks of embryonic red jungle fowl and black Sumatran bantam chickens (Gallus gallus).

Poultry science·2025
Same author

Cardiac mitochondria function in embryonic and 1-year old American alligators, Alligator mississippiensis, is not altered by hypoxic incubation or an acute anoxic challenge.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology·2025
Same author

Cardiovascular responses of embryonic alligator (Alligator mississippiensis) exposed to 10% O<sub>2</sub> and sodium cyanide (NaCN), a chemoreflex-inducing compound.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2025
Same journal

Integrated nutritional, antimicrobial, and transcriptomic analysis of the caudal gland in Sepiella inermis reveals a specialized bioactive defense organ.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026
Same journal

Disruption of Pik3r1 promotes muscle hyperplasia and lipolysis in grass carp (Ctenopharyngodon idella).

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026
Same journal

Methods: Novel use of mitochondrial function to optimize the permeabilization of crustacean gill types.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026
Same journal

Kisspeptin-2 stimulates testicular function in adult pejerrey (Odontesthes bonariensis): Does it act directly on the testes?

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026
Same journal

A single GPCR locus in Drosophila melanogaster partitions stress physiology by sex.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026
Same journal

Mechanisms underlying tolerance of severe hypoxia in sulfide spring fish.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026
See all related articles

Immature vertebrates have unique cardiovascular physiology distinct from adults. New research suggests incorporating developmental timelines and multivariate analysis for a more accurate understanding of the vertebrate heart and vasculature.

Area of Science:

  • Comparative physiology
  • Developmental biology
  • Cardiovascular science

Background:

  • Immature vertebrates (embryos, larvae, fetuses) exhibit distinct cardiovascular physiology compared to adults.
  • Current frameworks for studying developmental cardiovascular physiology are often conservative and rely on adult models.
  • Established physiological principles for adult cardiovascular systems may be inaccurate for developing systems.

Purpose of the Study:

  • To advocate for a modified conceptual framework for understanding developmental cardiovascular physiology.
  • To encourage a shift away from adult-centric physiological truisms in developmental studies.
  • To highlight the need for novel analytical approaches in comparative cardiovascular development.

Main Methods:

  • Emphasis on multivariate approaches for analyzing complex physiological data.

Related Experiment Videos

  • Differentiation between absolute (extrinsic) and relative (intrinsic) developmental time.
  • Employment of time lines for intra- and interspecific comparisons of cardiovascular ontogeny.

    • Main Results:

    • Current analytical approaches, often derived from adult physiology, may underappreciate the complexity of developing cardiovascular systems.
    • Incorporating specific methodologies can lead to a more accurate interpretation of cardiovascular development.
    • Novelty and complexity of the developing vertebrate cardiovascular system are often overlooked.

    Conclusions:

    • A revised conceptual framework is needed for developmental cardiovascular physiology.
    • Multivariate analysis, developmental time differentiation, and ontogenetic timelines are crucial for accurate research.
    • Adopting these approaches will enhance our understanding of the developing vertebrate cardiovascular system.