Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Altering plant-microbe interaction through artificially manipulating bacterial quorum sensing.

Rupert G Fray1

  • 1School of Biological Sciences, Nottingham University, Loughborough, UK. rupert.fray@nottingham.ac.uk

Annals of Botany
|July 5, 2002
PubMed
Summary

Bacteria use N-acylhomoserine lactones (AHLs) for cell-to-cell communication to coordinate group behaviors. Modifying plant AHL levels impacts bacterial infection susceptibility, offering new strategies for crop protection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ectopic expression of the transcriptional regulator and m6A writer complex member HIZ1 impacts development in Arabidopsis.

Plant physiology·2026
Same author

Functional and clinical significance of the RNA m<sup>6</sup>A methyltransferase complex in breast cancer.

NPJ breast cancer·2025
Same author

The functional and therapeutic potential of epitranscriptomics in breast cancer.

Epigenomics·2025
Same author

<i>Gluconacetobacter diazotrophicus</i> AZ0019 requires functional <i>nifD</i> gene for optimal plant growth promotion in tomato plants.

Frontiers in plant science·2024
Same author

The role of the ALKBH5 RNA demethylase in invasive breast cancer.

Discover oncology·2024
Same author

The importance of m<sup>6</sup>A topology in chicken embryo mRNA: a precise mapping of m<sup>6</sup>A at the conserved chicken β-actin zipcode.

RNA (New York, N.Y.)·2023

Area of Science:

  • Microbiology
  • Plant Science
  • Biochemistry

Background:

  • Bacteria communicate using signal molecules to regulate population density-dependent behaviors.
  • Quorum sensing, particularly using N-acylhomoserine lactones (AHLs) in Gram-negative bacteria, controls diverse physiological processes.
  • Plants can produce metabolites that interfere with bacterial AHL quorum sensing.

Purpose of the Study:

  • To investigate the role of AHL-mediated quorum sensing in plant-associated bacteria.
  • To explore the potential of manipulating plant AHL levels to alter bacterial infection.
  • To develop tools for understanding AHL-regulated behaviors in plant-microbe interactions.

Main Methods:

  • Engineering transgenic plants to produce or degrade AHLs.

Related Experiment Videos

  • Assessing the susceptibility of engineered plants to pathogenic Erwinia species.
  • Analyzing the impact of altered AHL signaling on bacterial behaviors.

    • Main Results:

    • Transgenic plants with modified AHL levels exhibited significantly altered susceptibility to pathogenic Erwinia species.
    • The study demonstrates a direct link between plant AHL manipulation and bacterial infection outcomes.
    • Engineered plants serve as valuable tools for dissecting AHL-regulated bacterial activities.

    Conclusions:

    • Plant-mediated modulation of bacterial quorum sensing is a viable strategy for controlling plant diseases.
    • Transgenic plants offer a novel approach to study and manage bacterial populations in agricultural settings.
    • Understanding AHL signaling is crucial for developing effective biological control and disease resistance in plants.