Stereotypic movement disorder after acquired brain injury
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Updated: Sep 30, 2026

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Published on: June 20, 2017
Cynthia M McGrath1, Richard E Kennedy, Wayne Hoye
1Methodist Rehabilitation Center, Jackson, Mississippi, USA.
Abstract:
Stereotypic movement disorder (SMD) consists of repetitive, non-functional motor behaviour that interferes with daily living or causes injury to the person. It is most often described in patients with mental retardation. However, recent evidence indicates that this condition is common among otherwise normal individuals. This case study describes a patient with new-onset SMD occurring after subdural haematoma and brain injury. SMD has rarely been reported after acquired brain injury, and none have documented successful treatment. The current psychiatric literature regarding neurochemistry, neuroanatomy, and treatment of SMD are reviewed with particular application to one patient. Treatment options include serotonin re-uptake inhibitors, opioid antagonists and dopamine antagonists. SMD has been under-appreciated in intellectually normal individuals, and may also be unrecognized after brain injury. Further investigation is needed in this area, which may benefit other individuals with SMD as well.
Insights
Stereotypic movement disorder (SMD) involves repetitive, non-functional motor behaviors. This case study highlights new-onset SMD after brain injury in an intellectually normal individual, suggesting it may be under-recognized.
Area of Science:
- Neuroscience
- Psychiatry
- Movement Disorders
Background:
- Stereotypic movement disorder (SMD) is characterized by repetitive, non-functional motor behaviors that impair daily life or cause self-injury.
- While often associated with intellectual disability, recent evidence suggests SMD is prevalent in intellectually normal individuals.
- Acquired brain injury is an under-recognized potential cause of new-onset SMD.
Observation:
- This case study details a patient who developed new-onset SMD following a subdural hematoma and subsequent brain injury.
- SMD following acquired brain injury is rarely reported, and successful treatment documentation is even scarcer.
- The patient was intellectually normal prior to the brain injury.
Findings:
- The study reviews current psychiatric literature on the neurochemistry, neuroanatomy, and treatment of SMD.
- Potential treatment options discussed include serotonin re-uptake inhibitors, opioid antagonists, and dopamine antagonists.
- This case demonstrates that SMD can occur in intellectually normal individuals after brain injury.
Implications:
- SMD may be under-recognized in intellectually normal populations and following acquired brain injuries.
- Further research into the neurobiological underpinnings and effective treatments for SMD in these populations is warranted.
- Understanding SMD after brain injury could lead to improved diagnostic and therapeutic strategies for affected individuals.
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