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Updated: Aug 19, 2026

Models of Bone Metastasis
Published on: September 4, 2012
[Analysis of factors affecting the prognosis of vertebral metastases]
T Riegel1, T Schilling, H Sitter
1Klinik für Neurochirurgie Philipps Universität Marburg, Germany. riegel@med.uni-marburg.de
Abstract:
The goal of this study was to evaluate factors for the prognosis of patients with metastatic spinal tumors. 139 patients with vertebral metastases were studied. The modified Tokuhashi Score (a preoperative score composed of six parameters) and single factors were analysed with statistical methods. The modified Tokuhashi Score showed a significant correlation (p = 0,0019) with survival time of patients. Additionally, only the Karnofsky Index as single parameter showed statistically significant correlation(p = 0.0016). Regarding the logistic regression, primary tumor, age, sex and Karnofsky Index were identified as prognostic factors for survival time. This trial could demonstrate that the Tokuhashi Score is a successful predicting tool for the assessment of prognosis of patients with vertebral metastases.
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