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Updated: Jul 26, 2026

Multifocal Electroretinograms
Published on: December 4, 2011
[Acute posterior multifocal placoid pigment epitheliopathy associated with Graves-Basedow's disease]
A T Ruiz Viñals1, J A Buil Calvo, O Martínez Giralto
1Hospital de la Esperanza y Hospital del Mar, Universidad Autónoma de Barcelona, Barcelona, España.
Clinical Case:
We present a case of a 40-years-old woman with an acute posterior multifocal placoid pigment epitheliopathy (APMPPE) associated with recent instauration hyperthyroidism symptoms. A Graves' disease was diagnosed and the patient was initially controlled with antithyroid drugs. The epitheliopathy evolution was relatively favourable without relapse. Two years later a thyroidectomy was performed.
Discussion:
We have not found in the literature any APMPPE case associated with Graves' disease. We only found an APMPPE case associated with a subacute thyroiditis. Little is known about the APMPPE causes, it could be that placoid epitheliopathy and Graves' disease had a common autoimmune origin. We can not forget that our finding could be only a matter of chance.
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